Phospho-GAB1 (Tyr627) Antibody - Cat. #: CSB-PA827140

SKU: CSB-PA827140

Size :100ul

Clone Number:

Aliases:Gab 1 antibody; GAB1 antibody; GAB1_HUMAN antibody; GRB 2 associated binder 1 antibody; GRB 2 associated binding protein 1 antibody; GRB2 associated binding protein 1 isoform a antibody; GRB2 associated binding protein 1 isoform b antibody; GRB2-associated binder 1 antibody; GRB2-associated-binding protein 1 antibody; Growth factor receptor bound protein 2-associated protein 1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q13480

Immunogen:Peptide sequence around phosphorylation site of tyrosine 627 (V-E-Y(p)-L-D) derived from Human Gab1.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IF; WB:1:500-1:1000, IF:1:100-1:200

Background:The protein encoded by Gab1 is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene.

Anders Kallin, et al. (2004) J. Biol. Chem ; 279: 17897 - 17904.
Hideto Kameda, et al. (2001) Cell Growth Differ ; 12: 307.
Masaki Osawa, et al. (2002) J. Cell Biol ; 158: 773.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Conjugate:Non-conjugated

Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:GAB1

Research Areas:Cancer;Cell biology;Signal transduction