Phospho-CLDN5 (Tyr217) Antibody - Cat. #: CSB-PA554477

SKU: CSB-PA554477

Size :100ul

Clone Number:

Aliases:Androgen withdrawal and apoptosis induced protein RVP1 like antibody; AWAL antibody; BEC 1 antibody; BEC1 antibody; Claudin 5 (transmembrane protein deleted in velocardiofacial syndrome) antibody; Claudin-5 antibody; Claudin5 antibody; CLD5_HUMAN antibody; CLDN 5 antibody; Cldn5 antibody; CPETR L1 antibody; CPETRL 1 antibody; CPETRL1 antibody; TMDVCF antibody; TMVCF antibody; Transmembrane protein deleted in VCFS antibody; Transmembrane protein deleted in velocardiofacial syndrome antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O00501

Immunogen:Peptide sequence around phosphorylation site of tyrosine 217 (K-K-N-Y(p)-V) derived from Human Claudin 5.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; IHC:1:50-1:100

Background:

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome.

Sirotkin H., Genomics 42:245-251(1997).
Collins J.E., Genome Biol. 5:RESEARCH84.1-RESEARCH84.11(2004).
The MGC Project Team; Genome Res. 14:2121-2127(2004).

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CLDN5

Research Areas:Signal transduction