Phospho-ATRIP (S224) Polyclonal Antibody

SKU: BT-PHS00813

Size:100μL

Background:ATRIP (ATR interacting protein) encodes an essential component of the DNA damage checkpoint. The encoded protein binds to single-stranded DNA coated with replication protein A. The protein also interacts with the ataxia telangiectasia and Rad3 related protein kinase, resulting in its accumulation at intranuclear foci induced by DNA damage. Multiple transcript variants encoding different isoforms have been found for ATRIP.

Research_area:Epigenetics and Nuclear Signaling

Target_protein:ATRIP

applications:WB, IHC-p, ELISA

Reactivity:Human

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Phospho-ATRIP (S224) Antibody

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):85838

UniProt accession:Human: Q8WXE1; Mouse: Q8BMG1

Synonyms:ATRIP; AGS1; ATR-interacting protein; ATM and Rad3-related-interacting protein

GeneID:Human: 84126