Pembrolizumab ELISA Kit

SKU: DS870048

Size:96T

Applications:ELISA

Accession:Q15116

Stability and Storage:The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.

Detection method:Colorimetric

Sample type:Plasma, Serum

Assay type:Quantitative

Sensitivity:0.156 μg/ml

Range:0.31-5 μg/mL

Recovery:80-120%

Properties:

Experimental Procedure:

Background:Pembrolizumab is an antibody drug that targets the cell surface receptor programmed cell death protein 1 (PD-1) found on T cells. By preventing the binding of its ligands (PD-L1 and PD-L2), pembrolizumab induces an antitumor immune response. Upregulation of PD-1 ligands is a mechanism for tumors to evade antitumor immune response; when PD-1 binds its ligand, the T cell receives an inhibitory signal leading to T cell anergy and blockade of anti-tumour immune response. Instead of directly targeting tumor tissue to induce tumor cell death, pembrolizumab acts as a checkpoint inhibitor to stimulate immune responses to eliminate cancer cells.

Alternative Names:MK-3475

Shipping:2-8 ℃

Note:For Research Use Only.