PDGFB Polyclonal Antibody

SKU: E-AB-70120

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:PDGFB

Target Synonym:Becaplermin;PDGF 2;PDGF B chain;PDGF subunit B;PDGF-2;PDGF2;Pdgfb;PDGFB;Platelet derived growth factor 2;Platelet-derived growth factor B chain;Platelet-derived growth factor beta polypeptide;Platelet-derived growth factor subunit B;Proto-oncogene c-Sis;SIS;SSV

Research Areas:Cancer;Cardiovascular;Metabolism;Developmental Biology;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Mouse;Rat

Application:WB;IHC;IF

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:

Accession:

Background:The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Concentration:410 μg/mL

Immunogen:KLH conjugated Synthetic peptide corresponding to Mouse PDGFB

Buffer:PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification method:Affinity purification

Dilution:WB 1:500-1:2000;IHC 1:200-1:400

Calculated MW:27kDa

ObservedMW:27kDa