PDGF-AA Polyclonal Antibody

SKU: AN005890L

Size::25μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles. Protected from prolonged exposure to light.

Shipping:The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:PDGF-AA

Target Synonym:PDGF A;PDGF A chain;Platelet derived growth factor alpha isoform 2 preproprotein;Platelet derived growth factor alpha polypeptide;PDGF1;PDGF-A;PDGFA;PDGF subunit A;PDGF-1;PDGF-AA;PDGFAA;Platelet Derived Growth Factor AA;Platelet derived growth factor alpha chain;Platelet-derived growth factor subunit A;Platelet-derived growth factor A chain;Platelet-derived growth factor alpha polypeptide

Research Areas:Cardiovascular;Signal Transduction;Immunology;Cancer;Metabolism;Developmental Biology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P04085

Accession:

Background:The platelet-derived growth factor (PDGF) family of disulfide-linked dimeric proteins consists of four homodimeric proteins, PDGF-AA, PDGF-BB, PDGF-CC and PDGF-DD, and one heterodimeric protein, PDGF-AB. Members of this protein family act mainly on connective tissue. The dimeric isoforms of PDGF are expressed by different cell types and at different times during embryonic development. All PDGF isoforms are synthesized as inactive precursors and are processed to active forms that contain a PDGF/VEGF cysteine knot domain. Only PDGF-C and PDGF-D, also named spinal cord-derived growth factors SCDGF and SCDGF-B, also contain an N-terminal CUB domain. Mature PDGF dimers bind and induce the homo- or hetero-dimerization of two receptor tyrosine kinases (PDGF R alpha and R beta).

Concentration:1 mg/mL

Immunogen:Recombinant Human PDGF-AA protein expressed by E.coli

Buffer:PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification method:Antigen Affinity Purification

Dilution:IHC 1:500-1:1000

Calculated MW:

ObservedMW: