PDE5A Polyclonal Antibody

SKU: BT-AP12876

Size:100μL

Background:This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.

Research_area:Cancer; Cardiovascular; Cell biology; Metabolism; Signal transduction

Target_protein:PDE5A

applications:WB, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:cGMP-specific 3',5'-cyclic phosphodiesterase

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: O76074; Mouse: Q8CG03; Rat: O54735

Synonyms:cGMP-specific 3',5'-cyclic phosphodiesterase ;EC 3.1.4.35;cGMP-binding cGMP-specific phosphodiesterase;CGB-PDE

GeneID:Human: 8654