PDE4B rabbit pAb

SKU: ES14187

Size: 100μL

Source:Rabbit

Applications:WB

Reactivity:Human;Rat

Dilution:WB 1：500-2000

Immunogen:Synthesized peptide derived from human PDE4B AA range: 103-153

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):

Human_gene_id:5142

Human_swiss_prot_no:Q07343

Subcellular_location:[Isoform PDE4B5]: Cytoplasm . Cell membrane .

Other_name:

Background:This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014],