PCBD1 Polyclonal Antibody

SKU: E-AB-19099

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: PCBD1

Target Synonym: 4 alpha hydroxy tetrahydropterin dehydratase;4-alpha-hydroxy-tetrahydropterin dehydratase;6 pyruvoyl tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1);6 pyruvoyl tetrahydropterin synthase/dimerization cofactor of hepatocyte nuclear factor 1 alpha;DCoH;Dimerization cofactor of hepatic nuclear factor 1 alpha;Dimerization cofactor of hepatocyte nuclear factor 1 alpha;Dimerization cofactor of hepatocyte nuclear factor 1-alpha;Dimerization cofactor of HNF1;Dimerizing cofactor for HNF1;PCBD 1;PCBD;PCBD1;PCD;Phenylalanine hydroxylase stimulating protein;Phenylalanine hydroxylase-stimulating protein;PHS;PHS;Pterin 4 alpha carbinolamine dehydratase;Pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1);Pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha;Pterin carbinolamine dehydratase;Pterin-4-alpha-carbinolamine dehydratase

Research Areas: Cancer;Epigenetics and Nuclear Signaling;Metabolism;Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P61457

Accession:

Background: This gene encodes a member of the pterin-4-alpha-carbinolamine dehydratase family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein functions as both a dehydratase involved in tetrahydrobiopterin biosynthesis, and as a cofactor for HNF1A-dependent transcription. A deficiency of this enzyme leads to hyperphenylalaninemia. Alternative splicing results in multiple transcript variants.

Concentration: 1.02 mg/mL

Immunogen: Fusion protein of human PCBD1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:500-1:2000;IHC 1:50-1:300

Calculated MW: 12 kDa

ObservedMW: Refer to figures