PAX6 antibody , Cat. # FNab06172

SKU: FNab06172

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells(By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains(By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes.

Immunogen:paired box 6

Synonyms:AN, AN2, Aniridia type II protein, D11S812E, MGDA, Oculorhombin, paired box 6, Paired box protein Pax 6, PAX6, WAGR

Observed MW:47kd

Uniprot ID:P26367

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, IHC, WB

Recommended dilution:WB: 1:300-1:1200; IHC: 1:50-1:500; IF: 1:50-1:500

Gene ID:5080

Research Area:Neuroscience, Stem Cells, Metabolism, Developmental biology