PADI4 Polyclonal Antibody

SKU: E-AB-52164

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: PADI4

Target Synonym: EC 3.5.3.15;HL 60 PAD;HL-60 PAD;PAD 4;PAD;PADI 4;PADI 5;PADI H protein;Padi4;PADI4;PADI5;PDI 4;PDI 5;PDI4;PDI5;Peptidyl arginine deiminase type IV;Peptidyl arginine deiminase type V;Peptidylarginine deiminase IV;Protein arginine deiminase;Protein arginine deiminase type 4;Protein arginine deiminase type IV;Protein-arginine deiminase type IV;Protein-arginine deiminase type-4

Research Areas: Cancer;Epigenetics and Nuclear Signaling;Metabolism;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q9UM07

Accession:

Background: This gene is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response. PADI4 plays a role in the epigenetics, the deimination of arginines on histones 3 and 4 can act antagonistically to arginine methylation. The protein may be found in oligomers and binds 5 calcium ions per subunit. It catalyses the reaction: Protein L-arginine + H2O = protein L-citrulline + NH3.

Concentration: 0.6 mg/mL

Immunogen: Fusion protein of human PADI4

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:500-1:2000;IHC 1:40-1:200

Calculated MW: 74 kDa

ObservedMW: Refer to figures