PACRG Rabbit Polyclonal Antibody

SKU: BT-AP11766

Size:100μL

Background:This gene encodes a protein that is conserved across metazoans. In vertebrates| this gene is linked in a head-to-head arrangement with the adjacent parkin gene| which is associated with autosomal recessive juvenile Parkinson's disease. These genes are co-regulated in various tissues and they share a bi-directional promoter. Both genes are associated with susceptibility to leprosy. The parkin co-regulated gene protein forms a large molecular complex with chaperones| including heat shock proteins 70 and 90| and chaperonin components. This protein is also a component of Lewy bodies in Parkinson's disease patients| and it suppresses unfolded Pael receptor-induced neuronal cell death. Multiple transcript variants encoding different isoforms have been found for this gene.

Research_area:Cell biology; Neuroscience

Target_protein:PACRG

applications:WB

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:PACRG

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):32560

UniProt accession:Human: Q96M98; Mouse: Q9DAK2

Synonyms:PACRG

GeneID:Human: 135138; Mouse: 69310