OCT4 Polyclonal Antibody

SKU: E-AB-68415

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:OCT4

Target Synonym:POU5F1;OCT3;OCT4;OTF-3;OTF3;OTF4;Oct-3;Oct-4

Research Areas:Cancer;Epigenetics and Nuclear Signaling;Developmental Biology;Stem Cells

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:WB;IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:Q01860

Accession:

Background:This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.

Concentration:1 mg/mL

Immunogen:A synthetic peptide of human OCT4

Buffer:PBS with 0.05% proclin300,50% glycerol,pH7.3.

Purification method:Affinity purification

Dilution:WB 1:500-1:2000;IHC 1:50-1:200

Calculated MW:30kDa/38kDa

ObservedMW:45KDa