OATP-C rabbit pAb

SKU: ES4514

Size: 100μL

Source:Rabbit

Applications:WB;ELISA

Reactivity:Human;Rat;Mouse;

Dilution:Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Immunogen:The antiserum was produced against synthesized peptide derived from human SLCO1B1. AA range:251-300

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):76kD

Human_gene_id:10599

Human_swiss_prot_no:Q9Y6L6

Subcellular_location:Basolateral cell membrane ; Multi-pass membrane protein . Detected in basolateral membranes of hepatocytes.

Other_name:SLCO1B1; LST1; OATP1B1; OATP2; OATPC; SLC21A6; Solute carrier organic anion transporter family member 1B1; Liver-specific organic anion transporter 1; LST-1; OATP-C; Sodium-independent organic anion-transporting polypeptide 2; OATP-2; Solut

Background:This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function. [provided by RefSeq, Mar 2009],