NSMCE3 Polyclonal Antibody

SKU: E-AB-16215

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: NDNL2

Target Synonym: HCA4;hepatocellular carcinoma-associated protein 4;hepatocellular carcinoma-associated protein HCA4;MAGE-G1 antigen;MAGEG1;MAGEL3;melanoma antigen;family G;1;melanoma-associated antigen G1;necdin-like 2;necdin-like gene 2;necdin-like protein 2;NSE3;NSMCE3

Research Areas: Cancer;Immunology

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: WB;IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q96MG7

Accession:

Background: The protein encoded by this gene is part of the SMC5-6 chromatin reorganizing complex and is a member of the MAGE superfamily. This is an intronless gene. Component of the SMC5-SMC6 complex, a complex involved in repair of DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. The complex is required for telomere maintenance via recombination in ALT (alternative lengthening of telomeres) cell lines and mediates sumoylation of shelterin complex (telosome) components which is proposed to lead to shelterin complex disassembly in ALT-associated PML bodies (APBs).

Concentration: 1.4 mg/mL

Immunogen: Synthetic peptide of human NDNL2

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:1000-1:5000;IHC 1:50-1:200

Calculated MW: 34kDa

ObservedMW: