NS Antibody, FITC conjugated - Cat. #: CSB-PA604972LC01IER

SKU: CSB-PA604972LC01IER

Size :50ul

Clone Number:

Aliases:NS antibody; Non-structural protein 1 antibody; NS1 antibody; NS1A antibody

Product Type:Polyclonal Antibody

Immunogen Species:Influenza A virus

UniProt ID:Q0HD54

Immunogen:Recombinant Influenza A virus Non-structural protein 1 protein (1-237AA)

Raised in:Rabbit

Species Reactivity:Influenza A virus

Tested Applications:

Background:Prevents the establishment of the cellular antiviral state by inhibiting TRIM25-mediated DDX58 ubiquitination, which normally triggers the antiviral transduction signal that leads to the activation of type I IFN genes by transcription factors IRF3 and IRF7. Prevents human EIF2AK2/PKR activation, either by binding double-strand RNA, or by interacting directly with EIF2AK2/PKR. This function may be important at the very beginning of the infection, when NS1 is mainly present in the cytoplasm. Also binds poly(A) and U6 snRNA.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:NS

Research Areas:N/A