NRAS/N-Ras Monoclonal Antibody

SKU: AN200076P

Size::

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies

Abbreviation:NRAS

Target Synonym:ALPS;HRAS;NRAS;ALPS4;CMNS;N-ras;NCMS;NRAS1;NS6;GTPase NRas;GTPase;HRAS1;RASN;Transforming protein N-Ras;AV095280;N ras;N ras protein part 4;Neuroblastoma RAS viral (v ras) oncogene homolog;OTTHUMP00000013879;OTTMUSP00000023521;Transforming protein N Ras;v ras neuroblastoma RAS viral oncogene homolog

Research Areas:Signal Transduction;Epigenetics and Nuclear Signaling;Cancer;Tags & Cell Markers

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:WB

Isotype:IgG1

Clonality:Monoclonal

Clone NO.:5B12

UNIProt ID:P01111

Accession:

Background:This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011]

Concentration:1 mg/mL

Immunogen:Recombinant Human NRAS / N-Ras Protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:WB 1:500-1:2000;

Calculated MW:21 kDa

ObservedMW:21 kDa