NPHS2 Antibody - Cat. #: CSB-PA172361

SKU: CSB-PA172361

Size :50ul

Clone Number:

Aliases:nephrosis 2 antibody; Nephrosis 2, idiopathic, steroid resistant (podocin) antibody; nephrosis 2, idiopathic, steroid resistant antibody; NPHS2 antibody; NPHS2 gene antibody; PDCN antibody; PODO_HUMAN antibody; Podocin antibody; SRN1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9NP85

Immunogen:Synthetic peptide of Human NPHS2

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200

Background:This gene encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN). SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:NPHS2

Research Areas:Cell biology;Tags & Cell Markers;Signal transduction