NOX4 Polyclonal Antibody

SKU: E-AB-70215

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:NOX4

Target Synonym:Kidney oxidase 1;Kidney oxidase-1;Kidney superoxide producing NADPH oxidase;Kidney superoxide-producing NADPH oxidase;KOX 1;KOX;Kox-1;KOX1;NADPH;NADPH oxidase 4;Nox4;NOX4;Renal NAD(P)H oxidase;Renal NAD(P)H-oxidase;RENOX

Research Areas:Cancer;Cell Biology;Cardiovascular;Metabolism;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:Q9NPH5,Q9JHI8,Q924V1

Accession:

Background:This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants.

Concentration:0.9 mg/mL

Immunogen:KLH conjugated Synthetic peptide corresponding to Mouse NOX4

Buffer:PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification method:Affinity purification

Dilution:WB 1:1000-1:2000;IHC 1:400-1:1000

Calculated MW:70kDa

ObservedMW:70kDa