NMDA Epsilon 1/2(Phospho Tyr1246/1252) Polyclonal Antibody

SKU: BT-AP07316

Size:100μL

Background:This gene encodes a member of the glutamate-gated ion channel protein family. The encoded protein is an N-methyl-D-aspartate (NMDA) receptor subunit. NMDA receptors are both ligand-gated and voltage-dependent, and are involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. These receptors are permeable to calcium ions, and activation results in a calcium influx into post-synaptic cells, which results in the activation of several signaling cascades. Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation. Alternative splicing results in multiple transcript variants.

Research_area:Neuroscience

Target_protein:GRIN2A

applications:WB, IHC-p, IF, ICC, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Glutamate [NMDA] receptor subunit epsilon-1/2

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):165283;166367

UniProt accession:Human: Q12879/Q13224; Rat: Q00959/Q00960

Synonyms:Glutamate [NMDA] receptor subunit epsilon-1/2; GRIN2A; NMDAR2A; Glutamate [NMDA; receptor subunit epsilon-1; N-methyl D-aspartate receptor subtype 2A; NMDAR2A; NR2A; hNR2A; GRIN2B; NMDAR2B; Glutamate [NMDA; receptor subunit epsilon-2; N-methyl D-aspartate receptor subtype 2B; NMDAR2B; N

GeneID:Human: 2903/2904; Mouse: 14811/14812; Rat: 24409/24410