NHRF1 Polyclonal Antibody

SKU: BT-AP13945

Size:100μL

Background:This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles| microvilli| and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2| and loss of heterozygosity of this gene is implicated in breast cancer.

Research_area:Signal transduction; Cancer; Tags & cell markers

Target_protein:SLC9A3R1

applications:WB, ELISA

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Na

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: O14745; Mouse: P70441; Rat: Q9JJ19

Synonyms:Na;+/H;+ exchange regulatory cofactor NHE-RF1 ;NHERF-1;Ezrin-radixin-moesin-binding phosphoprotein 50;EBP50;Regulatory cofactor of Na;+/H;+ exchanger;Sodium-hydrogen exchanger regulatory f

GeneID:Human: 9368