NFKBIB Monoclonal Antibody

SKU: BT-MCA2807

Size:100μL

Background:Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further IKBA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.Tissue specificity: Expressed in all tissues examined.

Research_area:Signal Transduction

Target_protein:NFKBIB

applications:WB

Reactivity:Human

Clonality:Monoclonal

Clone ID:7B4

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:NFKBIB

Immunogen:Purified recombinant fragment of human NFKBIB expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):45kDa

UniProt accession:Q15653

Synonyms:IKBB, TRIP9, NFKBIB

GeneID:4793