NDC80 Antibody - Cat. #: CSB-PA015601LA01HU

SKU: CSB-PA015601LA01HU

Size :50ug

Clone Number:

Aliases:from Entrez Gene , antibody; HEC antibody; Highly expressed in cancer antibody; Highly expressed in cancer protein antibody; Highly expressed in cancer rich in leucine heptad repeats antibody; HsHec1 antibody; hsNDC80 antibody; Kinetochore associated 2 antibody; Kinetochore associated protein 2 antibody; Kinetochore protein Hec1 antibody; Kinetochore protein NDC80 homolog antibody; Kinetochore-associated protein 2 antibody; KNTC2 antibody; ndc80 antibody; NDC80 homolog kinetochore complex component antibody; NDC80 kinetochore complex component homolog antibody; NDC80, S. cerevisiae, homolog of antibody; NDC80_HUMAN antibody; Retinoblastoma associated protein HEC antibody; Retinoblastoma-associated protein HEC antibody; TID3 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O14777

Immunogen:Recombinant Human Kinetochore protein NDC80 homolog protein (1-249AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity (PubMed:9315664, PubMed:12351790, PubMed:14654001, PubMed:14699129, PubMed:15062103, PubMed:15235793, PubMed:15239953, PubMed:15548592, PubMed:16732327). Required for kinetochore integrity and the organization of stable microtubule binding sites in the outer plate of the kinetochore (PubMed:15548592). The NDC80 complex synergistically enhances the affinity of the SKA1 complex for microtubules and may allow the NDC80 complex to track depolymerizing microtubules (PubMed:23085020).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:NDC80

Research Areas:Epigenetics and Nuclear Signaling; Cancer; Cell biology