NBR1 Monoclonal Antibody

SKU: E-AB-22148

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Monoclonal Antibodies

Abbreviation: NBR1

Target Synonym: 1A1 3B;1A13B;B box protein;Cell migration-inducing gene 19 protein;KIAA0049;M17S2;Membrane component chromosome 17 surface marker 2;Membrane component;chromosome 17;surface marker 2 (ovarian carcinoma antigen CA125);MIG 19;MIG19;Migration inducing protein 19;NBR 1;Nbr1;NBR1;autophagy cargo receptor;NBR1;Neighbor of BRCA1 gene 1;Neighbor of BRCA1 gene 1 protein;Next to BRCA1 gene 1 protein;Ovarian carcinoma antigen CA125;Protein 1A1-3B

Research Areas: Cancer;Cell Biology

Conjugation: Unconjugated

Host: Mouse

Species reactivity: Human;Mouse;Rat

Application: IHC-p;IF

Isotype: IgG

Clonality: Monoclonal

Clone NO.: Clone:4C6

UNIProt ID: Q14596

Accession:

Background: The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants.NBR1 (NBR1, Autophagy Cargo Receptor) is a Protein Coding gene. Diseases associated with NBR1 include Inclusion Body Myositis and Synucleinopathy. Among its related pathways are Mitophagy - animal. GO annotations related to this gene include ubiquitin binding and mitogen-activated protein kinase binding.

Concentration: 1 mg/mL

Immunogen: Recombinant Protein of NBR1

Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Purification method: Protein A purification

Dilution: IHC 1:50-300;IF 1:50-1:200

Calculated MW:

ObservedMW: