NBR1 (7C3) Mouse mAb

SKU: EM1373

Size: 100μL

Source:Mouse

Applications:IHC

Reactivity:Human, Mouse, Rat

Dilution:IHC 1:100-200

Immunogen:Recombinant Protein

Storage_stability:PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality:Monoclonal

Isotype:IgG1

Concentration:1mg/mL

Observed_band(KD):120kDa

Human_gene_id:4077

Human_swiss_prot_no:Q14596

Subcellular_location:Cytoplasm, Cytoplasmic vesicle, Lysosome

Other_name:1A13B, MIG19, Nbr1

Background:NBR1 protein is known for its encoding gene proximity to the BRCA1 tumor suppressor gene. N-terminal Phox and Bem1p (PB1) domains of NBR1 mediate its interaction with muscle specific titin kinase and scaffolding protein p62. NBR1 plays a role in autophagy by facilitating the autophagosomal degradation of ubiquitinated proteins independently and also in concert with p62.