NAMPT Antibody - Cat. #: CSB-PA015422EA01HU

SKU: CSB-PA015422EA01HU

Size :50ug

Clone Number:

Aliases:1110035O14Rik antibody; AI314458 antibody; AI480535 antibody; DKFZP666B131 antibody; EC 2.4.2.12 antibody; MGC117256 antibody; NAmPRTase antibody; Nampt antibody; NAMPT_HUMAN antibody; Nicotinamide phosphoribosyltransferase antibody; PBEF 1 antibody; PBEF antibody; PBEF1 antibody; Pre B cell colony enhancing factor 1 antibody; Pre B cell colony enhancing factor antibody; Pre B cell enhancing factor antibody; Pre-B cell-enhancing factor antibody; Pre-B-cell colony-enhancing factor 1 antibody; VF antibody; Visfatin antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P43490

Immunogen:Recombinant Human Nicotinamide phosphoribosyltransferase protein (1-280AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC, IF; Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200

Background:Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression (By similarity).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:NAMPT

Research Areas:Neuroscience; Cancer; Cardiovascular; Immunology; Metabolism; Signal transduction