N-cadherin antibody , Cat. # FNab05571

SKU: FNab05571

Size:100ug

Purification:Protein A+G purification

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Mouse

Clonality:monoclonal

Clone ID:1G1

Isotype:IgG2a

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density(By similarity).

Immunogen:cadherin 2, type 1, N-cadherin(neuronal)

Synonyms:Cadherin 2, CD325, CDH2, CDHN, CDw325, N cadherin, NCAD, N-cadherin, Neural cadherin

Observed MW:130 kDa

Uniprot ID:P19022

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, IHC, WB

Recommended dilution:WB: 1:1000-1:10000; IHC: 1:20-1:200

Gene ID:1000

Research Area:Signal Transduction, Cardiovascular, Immunology, Neuroscience, Stem Cells