MSX1 Monoclonal Antibody

SKU: BT-MCA3354

Size:100μL

Background:Drosophila,muscle segment (msh) homolog 1,homeo domain encoding gene,inhibiting MYOD1 expression,highly expressed in dental mesenchyme during critical bud stage,involved in epithelial-mesenchymal signaling in many organs,and in the pathogenesis of cleft lip and palate,interacting with MSX2 in mouse limb bud patterning .This gene encodes a member of the muscle segment homeobox gene family. The encoded protein functions as a transcriptional repressor during embryogenesis through interactions with components of the core transcription complex and other homeoproteins. It may also have roles in limb-pattern formation, craniofacial development, particularly odontogenesis, and tumor growth inhibition.Tissue specificity: Expressed in the developing nail bed mesenchyme.

Research_area:Epigenetics and nuclear signaling

Target_protein:MSX1

applications:WB

Reactivity:Human

Clonality:Monoclonal

Clone ID:5D11

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:MSX1

Immunogen:Purified recombinant fragment of human MSX1 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):31kDa

UniProt accession:P28360

Synonyms:HOX7, HYD1, STHAG1, MSX1

GeneID:4487