MSLN Monoclonal Antibody

SKU: BT-MCA3741

Size:100μL

Background:This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Research_area:Cancer, Tags & cell markers, Epigenetics and nuclear signaling

Target_protein:MSLN

applications:WB

Reactivity:

Clonality:Monoclonal

Clone ID:7E6A6

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:MSLN

Immunogen:Purified recombinant fragment of human MSLN (AA: 296-606) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):69kDa

UniProt accession:Q13421

Synonyms:MPF, SMRP

GeneID:10232