MRP-S18C Polyclonal Antibody

SKU: BT-AP05604

Size:100μL

Background:Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPS18C encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein mitochondrial ribosomal protein S18C is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 8p, 12p, 15q, and 22q.

Research_area:Others

Target_protein:MRPS18C

applications:WB, IHC-p, IF, ELISA

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:MRP-S18C Antibody

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):15850

UniProt accession:Human: Q9Y3D5; Mouse: Q8R2L5

Synonyms:MRPS18C; CGI-134; 28S ribosomal protein S18c; mitochondrial; MRP-S18-c; Mrps18-c; S18mt-c; 28S ribosomal protein S18-1, mitochondrial; MRP-S18-1

GeneID:Human: 51023; Mouse: 68735