MRP-L12 rabbit pAb

SKU: ES2828

Size: 100μL

Source:Rabbit

Applications:WB;ELISA;IHC

Reactivity:Human;Mouse

Dilution:WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000

Immunogen:The antiserum was produced against synthesized peptide derived from human MRPL12. AA range:31-80

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):21kD

Human_gene_id:6182

Human_swiss_prot_no:P52815

Subcellular_location:Mitochondrion .

Other_name:MRPL12; RPML12; 39S ribosomal protein L12; mitochondrial; L12mt; MRP-L12; 5c5-2

Background:Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which forms homodimers. In prokaryotic ribosomes, two L7/L12 dimers and one L10 protein form the L8 protein complex. [provided by RefSeq, Jul 2008],