MRAP2 antibody , Cat. # FNab05304

SKU: FNab05304

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Modulator of melanocortin receptor 4(MC4R), a receptor involved in energy homeostasis. Plays a central role in the control of energy homeostasis and body weight regulation by increasing ligand-sensitivity of MC4R and MC4R-mediated generation of cAMP(By similarity). May also act as a negative regulator of MC2R: competes with MRAP for binding to MC2R and impairs the binding of corticotropin(ACTH) to MC2R. May also regulate activity of other melanocortin receptors(MC1R, MC3R and MC5R); however, additional evidences are required in vivo.

Immunogen:melanocortin 2 receptor accessory protein 2

Synonyms:C6orf117

Observed MW:

Uniprot ID:Q96G30

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, IHC

Recommended dilution:IHC: 1:20-1:200

Gene ID:112609

Research Area:Neuroscience, Signal Transduction, Immunology