MPP1 rabbit pAb

SKU: ES8068

Size: 100μL

Source:Rabbit

Applications:IF;ELISA;IHC

Reactivity:Human;Rat;Mouse;

Dilution:IF/ICC 1:50-300; ELISA 1:2000-20000; IHC-p 1:50-200

Immunogen:The antiserum was produced against synthesized peptide derived from human KIF20B. AA range:1771-1820

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):210kD

Human_gene_id:9585

Human_swiss_prot_no:Q96Q89

Subcellular_location:Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Nucleus, nucleolus . Nucleus, nucleoplasm . Cytoplasm, cytoskeleton, spindle . Cytoplasm, cytoskeleton, spindle pole . Midbody . Cell projection, axon . Cell projection, growth cone . Localizes mainly in the nucleus during interphase although it is also detected in the cytoplasm without clear association with microtubules (PubMed:12740395). Localized to the central spindle during cytokinetic furrowing and with the midbody during abscission (PubMed:12740395, PubMed:17409436). A 2-3 fold expression increase is seen as cells progress from G1 to G2/M phase (PubMed:12740395). During prophase and metaphase it is found throughout the cytoplasm and at anaphase accumulates at the midplan of the cell and forms a distinct

Other_name:KIF20B; KRMP1; MPHOSPH1; Kinesin-like protein KIF20B; Cancer/testis antigen 90; CT90; Kinesin-related motor interacting with PIN1; M-phase phosphoprotein 1; MPP1

Background:KIF20B (Kinesin Family Member 20B) is a Protein Coding gene. Among its related pathways are Golgi-to-ER retrograde transport and Factors involved in megakaryocyte development and platelet production. GO annotations related to this gene include ATPase activity and microtubule motor activity. An important paralog of this gene is KIF23.