Mouse Transcription Factor Sp1, SP1 ELISA Kit

SKU: E2519Mo

Size:96 Tests-1 Kit

Background:Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter Plays an essential role in the regulation of FE65 gene expression (By similarity). Positively regulates the transcription of the core clock component ARNTL/BMAL1 (PubMed: 24030830). Plays a role in protecting cells against oxidative stress following brain injury by regulating the expression of RNF112 (PubMed: 27918959).

Research_area:Others

Applications:ELISA

Target_protein:SP1

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:9.69ng/L

Detection range:20-6000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Transcription Factor Sp1

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O89090

MASS(Da):80,732

GeneID:20683

Synonyms:SP 1;SP1;Specificity protein 1;Transcription factor Sp1

Gene names:SP1

Standard solution:6400ng/L