Mouse Thrombopoietin/TPO ELISA Kit PicoKine®

SKU: EK0517

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Mouse

Applications: ELISA

Application Details:

Gene Name: TPO

Specificity: Natural and recombinant mouse TPO

Background: Thrombopoietin (TPO) is also called megakaryocyte growth and development factor (MGDF). TPO, a lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from committed progenitor cells, is believed to be the major physiological regulator of circulating platelet levels. Human, dog, and mouse cDNAs for MGDF are highly conserved and encode open reading frames for proteins of 353, 352, and 356 amino acids, respectively, including predicted signal peptides. MGDF is a novel cytokine that regulates megakaryocyte development and is a ligand for the MPL receptor. The human MGDF gene has been mapped to chromosome 3q26.3. The standard product used in this kit is gene recombinant mouse TPO, consisting of 335 amino acids with the molecular mass of 35KDa. As a result of glycosylation, the molecular mass is 75KDa.

Immunogen: Expression system for standard: NS0; Immunogen sequence: S22-T356

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Reference:

Uniprot ID: P40226

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 21832

Protein Name: Thrombopoietin

Gene Full Name: thrombopoietin

Synonyms: thrombopoietin; MGDF; MKCSF; ML; MPLLG; THCYT1; TPO; Thpo