Mouse Steroid 21-hydroxylase,CYP21B ELISA KIT

SKU: E0820Mo

Size:96 Tests-1 Kit

Background:A cytochrome P450 monooxygenase that plays a major role in adrenal steroidogenesis. Catalyzes the hydroxylation at C-21 of progesterone and 17alpha-hydroxyprogesterone to respectively form 11-deoxycorticosterone and 11-deoxycortisol, intermediate metabolites in the biosynthetic pathway of mineralocorticoids and glucocorticoids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). {ECO:0000250|UniProtKB:P00191, ECO:0000250|UniProtKB:P08686}.

Research_area:

Applications:ELISA

Target_protein:Cyp21

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.62ng/ml

Detection range:1.25-80ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Cytochrome P450 21B

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P03940

MASS(Da):55328

GeneID:13079

Synonyms:Cyp21 Cyp21a-1 Cyp21a1

Gene names:Cyp21

Standard solution:160ng/ml