Mouse SPRY domain-containing SOCS box protein 2,SPSB2 ELISA KIT

SKU: E1235Mo

Size:96 Tests-1 Kit

Background:Substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:20603330). Negatively regulates nitric oxide (NO) production and limits cellular toxicity in activated macrophages by mediating the ubiquitination and proteasomal degradation of NOS2 (PubMed:20603330). Acts as a bridge which links NOS2 with the ECS E3 ubiquitin ligase complex components ELOC and CUL5 (By similarity). {ECO:0000250|UniProtKB:Q99619, ECO:0000269|PubMed:20603330}.

Research_area:

Applications:ELISA

Target_protein:Spsb2

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.1ng/ml

Detection range:0.19-12ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:SPRY domain-containing SOCS box protein 2

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O88838

MASS(Da):28938

GeneID:14794

Synonyms:Spsb2 Grcc9 Ssb2

Gene names:Spsb2

Standard solution:24ng/ml