Mouse SPRY domain-containing SOCS box protein 1,SPSB1 ELISA KIT

SKU: E1234Mo

Size:96 Tests-1 Kit

Background:Substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Negatively regulates nitric oxide (NO) production and limits cellular toxicity in activated macrophages by mediating the ubiquitination and proteasomal degradation of NOS2 (By similarity). Acts as a bridge which links the NOS2 with the ECS E3 ubiquitin ligase complex components ELOC and CUL5 (By similarity). {ECO:0000250|UniProtKB:Q96BD6}.

Research_area:

Applications:ELISA

Target_protein:Spsb1

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.08ng/ml

Detection range:0.19-12ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:SPRY domain-containing SOCS box protein 1

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9D5L7

MASS(Da):30785

GeneID:74646

Synonyms:Spsb1 Ssb1

Gene names:Spsb1

Standard solution:24ng/ml