Mouse/Rat DCC ELISA Kit PicoKine®

SKU: EK2184

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Mouse,Rat

Applications: ELISA

Application Details:

Gene Name: Dcc

Specificity: Natural and recombinant Mouse/Rat DCC

Background: Netrin receptor DCC, also known as DCC, or colorectal cancer suppressor is a protein which in humans is encoded by the DCC gene. Predicted to enable identical protein binding activity; netrin receptor activity; and transcription coactivator activity. Involved in postsynaptic modulation of chemical synaptic transmission. Acts upstream of or within generation of neurons. Located in axon. Is integral component of postsynaptic density membrane. Is active in Schaffer collateral - CA1 synapse. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; lung; and retina. Human ortholog(s) of this gene implicated in colorectal cancer; congenital mirror movement disorder; esophageal cancer; and esophagus squamous cell carcinoma. Orthologous to human DCC (DCC netrin 1 receptor).

Immunogen: Expression system for standard: NS0; Immunogen sequence: F32-N1097

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Reference:

Uniprot ID: P70211/Q63155

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 13176, 25311

Protein Name:

Gene Full Name:

Synonyms: Colorectal cancer suppressor; CRC18; CRCR1; DCC; IGDCC1; Netrin receptor DCC; Tumor suppressor protein DCC