Mouse Ras-related Protein Rab-1A, RAB1A ELISA Kit

SKU: E2417Mo

Size:96 Tests-1 Kit

Background:The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes (PubMed:20639577, PubMed:22854043). Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (PubMed:20639577, PubMed:22854043). RAB1A regulates vesicular protein transport from the endoplasmic reticulum (ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secretion (By similarity). Regulates the level of CASR present at the cell membrane (By similarity). Plays a role in cell adhesion and cell migration, via its role in protein trafficking (PubMed:20639577). Plays a role in autophagosome assembly and cellular defense reactions against pathogenic bacteria (By similarity). Plays a role in microtubule-dependent protein transport by early endosomes and in anterograde melanosome transport (PubMed:22854043).

Research_area:Signal Transduction

Applications:ELISA

Target_protein:RAB1A

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:7.23ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Ras-related protein Rab-1A

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P62821

MASS(Da):22,678

GeneID:19324

Synonyms:Gtb;Gtbp;mKIAA3012;Ra;Rab;Rab1;Rab-1;RAB1A;Ras-related protein Rab-1A;Ypt;YPT1-related protein

Gene names:Rab1A

Standard solution:3200ng/L