Mouse R-Spondin-4, RSPO4 ELISA Kit

SKU: E2437Mo

Size:96 Tests-1 Kit

Background:Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway.

Research_area:Others

Applications:ELISA

Target_protein:RSPO4

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:9.86ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:R-spondin-4

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q8BJ73

MASS(Da):25,866

GeneID:228770

Synonyms:A730099F22;A930029K19Rik;Cristin-4;Cysteine-rich and single thrombospondin domain-containing protein 4;mCristin-4;Roof plate-specific spondin-4;RSPO4;R-spondin-4

Gene names:Rspo4

Standard solution:4800ng/L