Mouse Protein Wnt-7a,WNT7A ELISA KIT

SKU: E2404Mo

Size:96 Tests-1 Kit

Background:Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta-catenin signaling pathway (PubMed:18230341, PubMed:20530549, PubMed:23629626). Plays an important role in embryonic development, including dorsal versus ventral patterning during limb development, skeleton development and urogenital tract development (PubMed:7885472, PubMed:9769174, PubMed:9790192). Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation (PubMed:28803732). Required for normal, sexually dimorphic development of the Mullerian ducts, and for normal fertility in both sexes (PubMed:9790192). Required for normal neural stem cell proliferation in the hippocampus dentate gyrus (PubMed:23629626). Required for normal progress through the cell cycle in neural progenitor cells, for self-renewal of neural stem cells, and for normal neuronal differentiation and maturation (PubMed:23629626). Promotes formation of synapses via its interaction with FZD5 (PubMed:20530549). {ECO:0000269|PubMed:18230341, ECO:0000269|PubMed:20530549, ECO:0000269|PubMed:23629626, ECO:0000269|PubMed:28803732, ECO:0000269|PubMed:7885472, ECO:0000269|PubMed:9769174, ECO:0000269|PubMed:9790192}.

Research_area:

Applications:ELISA

Target_protein:Wnt7a

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.019ng/mL

Detection range:0.05-20ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Protein Wnt-7a

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P24383

MASS(Da):38974

GeneID:22421

Synonyms:Wnt7a Wnt-7a

Gene names:Wnt7a

Standard solution:24ng/mL