Mouse Osteoprotegerin, OPG ELISA Kit

SKU: E0110Mo

Size:96 Tests-1 Kit

Background:Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis.

Research_area:Cell Biology

Applications:ELISA

Target_protein:TNFRSF11B

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:5.45ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Osteoprotegerin

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O08712

MASS(Da):45,923

GeneID:18383

Synonyms:Osteoclastogenesis inhibitory factor;Osteoprotegerin;TNFRSF 11B;TNFRSF11B;Tumor necrosis factor receptor superfamily member 11B

Gene names:TNFRSF11B

Standard solution:2400ng/L