Mouse Niemann-Pick C1-like protein 1,NPC1L1 ELISA KIT

SKU: E2309Mo

Size:96 Tests-1 Kit

Background:Plays a major role in cholesterol homeostasis. Is critical for the uptake of both phytosterol and cholesterol across the plasma membrane of the intestinal enterocyte. Is the direct molecular target of ezetimibe, a drug that inhibits cholesterol absorption (By similarity). The protein may have a function in the transport of multiple lipids and their homeostasis, and may play a critical role in regulating lipid metabolism. Acts as a negative regulator of NPC2 and down-regulates its expression and secretion by inhibiting its maturation and accelerating its degradation (By similarity). {ECO:0000250, ECO:0000269|PubMed:14976318, ECO:0000269|PubMed:15173162, ECO:0000269|PubMed:15671032}.

Research_area:

Applications:ELISA

Target_protein:Npc1l1

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:5.29ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Niemann-Pick C1-like protein 1

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q6T3U4

MASS(Da):147132

GeneID:

Synonyms:Npc1l1

Gene names:Npc1l1

Standard solution:2400ng/L