Mouse Interferon Regulatory Factor 4, IRF4 ELISA Kit

SKU: E2162Mo

Size:96 Tests-1 Kit

Background:Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes.

Research_area:Others

Applications:ELISA

Target_protein:IRF4

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:5.34ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Interferon Regulatory Factor 4

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q64287

MASS(Da):51,577

GeneID:16364

Synonyms:Interferon regulatory factor 4;IRF 4;IRF4;IRF-4;LSIRF;Lymphocyte-specific interferon regulatory factor;NF-EM5;PU.1 interaction partner;Transcriptional activator PIP;

Gene names:IRF4

Standard solution:2400ng/L