Mouse Inositol Polyphosphate-4-Phosphatase type I 107 kDa,INPP4A ELISA KIT

SKU: E1608Mo

Size:96 Tests-1 Kit

Background:Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate (PubMed:20463662). Catalyzes also inositol 1,3,4-trisphosphate and inositol 1,4-bisphosphate (By similarity). Antagonizes the PI3K-AKT/PKB signaling pathway by dephosphorylating phosphoinositides and thereby modulating cell cycle progression and cell survival (PubMed:11087841, PubMed:19325558). May protect neurons from excitotoxic cell death by regulating the synaptic localization of cell surface N-methyl-D-aspartate-type glutamate receptors (NMDARs) and NMDAR-mediated excitatory postsynaptic current (PubMed:20463662). {ECO:0000250|UniProtKB:Q62784, ECO:0000269|PubMed:11087841, ECO:0000269|PubMed:19325558, ECO:0000269|PubMed:20463662}.

Research_area:

Applications:ELISA

Target_protein:Inpp4a

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.01ng/ml

Detection range:0.05-10ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Inositol Polyphosphate-4-Phosphatase type I 107 kDa

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9EPW0

MASS(Da):105540

GeneID:269180

Synonyms:Inpp4a

Gene names:Inpp4a

Standard solution:12.8ng/ml