Mouse IL-17F/Interleukin-17F ELISA Kit PicoKine®

SKU: EK0796

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Mouse

Applications: ELISA

Application Details:

Gene Name: IL17F

Specificity: Natural and recombinant mouse IL-17F

Background: Interleukin 17F, also called IL17F is involved in the regulation of normal versus aberrant T-cell responses. This gene is mapped to 6p12.2. The protein encoded by this gene is a cytokine that shares sequence similarity with IL17. This cytokine is expressed by activated T cells, and has been shown to stimulate the production of several other cytokines, including IL6, IL8, and CSF2/GM_CSF. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL2, TGFB1/TGFB, and monocyte chemoattractant protein-1. It is suggested that targeting IL17 and IL17F or antagonizing IL17R might mitigate neutrophil-mediated inflammation in CF.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: R21-A153

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Uniprot ID: Q7TNI7

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 257630

Protein Name: Interleukin-17F

Gene Full Name: interleukin 17F

Synonyms: Cytokine ML 1; IL 17F; IL17F; IL-17F; interleukin 17F; ML 1; ML1