Mouse IGF-2 ELISA Kit PicoKine®

SKU: EK0381

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Mouse

Applications: ELISA

Application Details:

Gene Name: IGF2

Specificity: Natural and recombinant mouse IGF-2

Background: Insulin-like growth factor II is also known as somatomedin A. IGF-2 is a member of the insulin family of polypeptide growth factors that is involved in development and growth. It is paternally expressed in the fetus and placenta. IGF-II is a mitogen for many cell types and an important modulator of muscle growth and differentiation. IGF-II gene is prevalently expressed during prenatal development and its gene activity is regulated by genomic imprinting, in that the allele inherited from the father is active and the allele inherited from the mother is inactive in most normal tissues. IGF-II appears to be induced by placental lactogen during prenatal development. It is a mediator of prolactin-induced alveologenesis; prolactin, IGF-2, and cyclin D1, all of which are overexpressed in breast cancers, are components of a developmental pathway in the mammary gland.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: A25-E91

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Reconstitution:

Reference:

Uniprot ID: P09535

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Cross Reactivity: There is no detectable cross-reactivity with IGF-1.

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Gene ID: 16002

Protein Name: Insulin-like growth factor 2

Gene Full Name: insulin-like growth factor 2

Synonyms: insulin like growth factor 2; C11orf43; GRDF; IGF-II; PP9974; SRS3; IGF-2; IGF2