Mouse Growth Factor Receptor-Bound Protein 2, GRB2 ELISA Kit

SKU: E2656Mo

Size:96 Tests-1 Kit

Background:Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. [Isoform 2]: Does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element. Acts as a dominant negative protein over GRB2 and by suppressing proliferative signals, may trigger active programmed cell death.

Research_area:Signal Transduction

Applications:ELISA

Target_protein:GRB2

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:11.66ng/L

Detection range:20-3800ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Growth Factor Receptor-Bound Protein 2

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q60631

MASS(Da):25,238

GeneID:14784

Synonyms:Adapter protein GRB2;GRB 2;GRB2;Growth factor receptor-bound protein 2;SH2/SH3 adapter GRB2

Gene names:GRB2

Standard solution:4000ng/L