Mouse GATA binding protein 4,GATA4 ELISA KIT

SKU: E0428Mo

Size:96 Tests-1 Kit

Background:Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development (By similarity). In cooperation with TBX5, it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression, while it downregulates endocardial and endothelial gene expression (By similarity). Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression (By similarity). Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions (By similarity). Acts as a transcriptional activator of ANF in cooperation with NKX2-5 (PubMed:9584153). Promotes cardiac myocyte enlargement (By similarity). Required during testicular development (By similarity). May play a role in sphingolipid signaling by regulating the expression of sphingosine-1-phosphate degrading enzyme, sphingosine-1-phosphate lyase (By similarity). {ECO:0000250|UniProtKB:P43694, ECO:0000250|UniProtKB:P46152, ECO:0000269|PubMed:9584153}.

Research_area:

Applications:ELISA

Target_protein:Gata4

Reactivity:Mouse

Assay type:Sandwich

Sensitivity:0.19ng/ml

Detection range:0.38-24ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:GATA binding protein 4

Species:Mouse

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q08369

MASS(Da):44580

GeneID:14463

Synonyms:Gata4 Gata-4

Gene names:Gata4

Standard solution:48ng/ml